Sepsis or, more commonly, blood poisoning causes more deaths than prostate cancer, breast cancer, and AIDS combined. 30 million people get sepsis every year, and 20 people die from it every minute. Sepsis is the body’s extreme response to an infection. It happens when an infection you already have, for example in your lungs, triggers a chain reaction throughout your body.
Sepsis is life-threatening, and without timely treatment, it can cause organ failure and death. Antimicrobial therapy is a key element in treatment – in septic shock, the initiation of antibiotic therapy within one hour increases survival; with each hour antibiotic therapy is delayed, survival decreases by about 8% (Kumar et al. Crit Care Med. 2006)